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Phase IInterventional

An Open-Label Evaluation Phase 1 Trial of the Safety and Pharmacokinetics of MRX-2843 in Adolescents and Adults With Relapsed/Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Mixed Phenotype Acute Leukemia

Protocol: STUDY00002843NCT: NCT04872478

Overview

Primary Objective:

  • To evaluate the safety and tolerability and establish the Recommended Phase 2 dose (RP2D) of orally-administered (PO) MRX-2843 in patients with relapsed/refractory acute myeloid leukemia, acute lymphoblastic leukemia, or mixed phenotype acute leukemia.

Secondary Objectives:

  • To evaluate the pharmacokinetics and efficacy of MRX-2843 in patients with relapsed/refractory acute myeloid leukemia, acute lymphoblastic leukemia, or mixed phenotype acute leukemia
Investigators
Location
Winship Cancer Institute
View on ClinicalTrials.gov